Cyclopia is a rare congenital disorder with life-threatening complications.
Early diagnosis during pregnancy should be emphasized to prevent its complications.
Early diagnosis is important to allow for early termination of pregnancy and to minimize the physiological and psychological impact of such anomalies on the mother and family.
Introduction and importance: Cyclopia is a rare congenital disorder characterized by facial abnormalities. It is the most severe form of alobar holoprosencephaly. This syndrome affects the embryos that are either aborted or stillborn upon delivery or, at best, die shortly after birth.
Case report: Patient aged 27 years, third gesture, third pare, admitted for premature delivery of 7 months. After labor management, she gave birth 4 h after admission to the maternity ward of a living newborn female weighing 1100 g. The newborn's Apgar score could not be calculated. In the initial physical examination, an eye and a 4-cm proboscis were seen in the middle of the forehead. The newborn had no nose, and his outer ears were normal.
Clinical discussion: Cyclopia is a rare deformity. It is considered to results from the fusion of two optic grooves, because of defective development of the ventral diencephalon (holoprosencephaly).
Conclusion: Prenatal diagnosis by ultrasound examination might help in the detection of cyclopia and in the prevention of complications associated with such a condition.
Keywords: Case report; Cyclopia; Holoprosencephaly; Newborn.