Recent Progress on Nanocrystalline Metallic Materials for Biomedical Applications

Huafang Li; Pengyu Wang; Cuie Wen

doi:10.3390/nano12122111

Recent Progress on Nanocrystalline Metallic Materials for Biomedical Applications

Nanomaterials (Basel). 2022 Jun 19;12(12):2111. doi: 10.3390/nano12122111.

Authors

Huafang Li¹, Pengyu Wang¹, Cuie Wen²

Affiliations

¹ School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.
² School of Engineering, RMIT University, Melbourne, VIC 3001, Australia.

Abstract

Nanocrystalline (NC) metallic materials have better mechanical properties, corrosion behavior and biocompatibility compared with their coarse-grained (CG) counterparts. Recently, nanocrystalline metallic materials are receiving increasing attention for biomedical applications. In this review, we have summarized the mechanical properties, corrosion behavior, biocompatibility, and clinical applications of different types of NC metallic materials. Nanocrystalline materials, such as Ti and Ti alloys, shape memory alloys (SMAs), stainless steels (SS), and biodegradable Fe and Mg alloys prepared by high-pressure torsion, equiangular extrusion techniques, etc., have better mechanical properties, superior corrosion resistance and biocompatibility properties due to their special nanostructures. Moreover, future research directions of NC metallic materials are elaborated. This review can provide guidance and reference for future research on nanocrystalline metallic materials for biomedical applications.

Keywords: biocompatibility; biomedical applications; corrosion behavior; mechanical properties; nanocrystalline metallic materials.

Publication types

Review

Grants and funding

This work was funded by the National Natural Science Foundation of China, China (grant No. 31700819), the Young Elite Scientists Sponsorship Program by CAST (YESS, grant No. 2018QNRC001) and the Fundamental Research Funds for the Central Universities and the Youth Teacher International Exchange and Growth Program (No. QNXM20210021).