The Untapped Potential of Ginsenosides and American Ginseng Berry in Promoting Mental Health via the Gut-Brain Axis

Nutrients. 2022 Jun 17;14(12):2523. doi: 10.3390/nu14122523.

Abstract

Despite the popularity of the ginseng (Panax) root in health research and on the market, the ginseng berry's potential remains relatively unexplored. Implementing ginseng berry cultivations and designing berry-derived products could improve the accessibility to mental health-promoting nutraceuticals. Indeed, the berry could have a higher concentration of neuroprotective and antidepressant compounds than the root, which has already been the subject of research demonstrating its efficacy in the context of neuroprotection and mental health. In this review, data on the berry's application in supporting mental health via the gut-brain axis is compiled and discussed.

Keywords: ginseng berry; ginsenosides; gut microbiota; gut–brain axis; mental health; nutraceutical.

Publication types

  • Review

MeSH terms

  • Brain-Gut Axis
  • Fruit
  • Ginsenosides* / pharmacology
  • Mental Health
  • Panax*

Substances

  • Ginsenosides

Grants and funding

This research received no external funding.