Very-Low-Dose Radiation and Clinical Molecular Nuclear Medicine

Life (Basel). 2022 Jun 17;12(6):912. doi: 10.3390/life12060912.

Abstract

Emerging molecular and precision medicine makes nuclear medicine a de facto choice of imaging, especially in the era of target-oriented medical care. Nuclear medicine is minimally invasive, four-dimensional (space and time or dynamic space), and functional imaging using radioactive biochemical tracers in evaluating human diseases on an anatomically configured image. Many radiopharmaceuticals are also used in therapies. However, there have been concerns over the emission of radiation from the radionuclides, resulting in wrongly neglecting the potential benefits against little or any risks at all of imaging to the patients. The sound concepts of radiation and radiation protection are critical for promoting the optimal use of radiopharmaceuticals to patients, and alleviating concerns from caregivers, nuclear medicine staff, medical colleagues, and the public alike.

Keywords: nuclear medicine; protection; radiation; radionuclides; risks; therapy.

Publication types

  • Review

Grants and funding

This study was financially supported by the Ministry of Science and Technology, R.O.C. (MOST 109-2314-B-038-151 and B-075-052-MY2, MOST 110-2314-B-038-167), the Higher Education Sprout Project by the Ministry of Education (MOE) in Taiwan (DP2-111-21121-01-C-03-03), and Taipei Medical University Hospital (110TMU-TMUH-02-3, TMU109-AE1-B27, 110-AE1-B26).