Hypervirulent Clostridioides difficile RT078 lineage isolates from the river: A potential reservoir for environmental transmission

Chin-Shiang Tsai; Ya-Lien Cheng; Jung-Sheng Chen; Pei-Jane Tsai; Bo-Yang Tsai; Bing-Mu Hsu; I-Hsiu Huang

doi:10.1016/j.jmii.2022.05.002

Hypervirulent Clostridioides difficile RT078 lineage isolates from the river: A potential reservoir for environmental transmission

J Microbiol Immunol Infect. 2022 Oct;55(5):977-981. doi: 10.1016/j.jmii.2022.05.002. Epub 2022 Jun 4.

Authors

Chin-Shiang Tsai¹, Ya-Lien Cheng², Jung-Sheng Chen³, Pei-Jane Tsai⁴, Bo-Yang Tsai⁵, Bing-Mu Hsu⁶, I-Hsiu Huang⁷

Affiliations

¹ Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital, Dou-Liou Branch, College of Medicine, National Cheng Kung University, Yunlin, Taiwan; Department of Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
² Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
³ Department of Medical Research, E-Da Hospital, Kaohsiung City, Taiwan.
⁴ Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁵ Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁶ Department of Earth and Environmental Sciences, National Chung Cheng University, Chiayi, Taiwan.
⁷ Department of Biochemistry and Microbiology, Oklahoma State University Center for Health Sciences, USA. Electronic address: george.huang@okstate.edu.

PMID: 35739056
DOI: 10.1016/j.jmii.2022.05.002

Abstract

This is the first report to discover Clostridiodes difficile (C. difficile) ribotype RT126 and RT598 (both ribotypes belong to RT078-lineage) in a river water system in southern Taiwan. Fluoroquinolone resistance was also found. The connection between clinical isolates and those from the environment needs further investigation.

Keywords: Clostridioides (Clostridium) difficile; RT126; RT598; River; Taiwan.

MeSH terms

Clostridioides
Clostridioides difficile* / genetics
Fluoroquinolones / pharmacology
Humans
Rivers
Water

Substances

Fluoroquinolones
Water