On the dielectric and mechanical characterization of tissue-mimicking breast phantoms

Abstract

Objective. In this paper, we focus on the dielectric and mechanical characterization of tissue-mimicking breast phantoms.Approach. Starting from recipes previously proposed by our research group, based on easy-to-handle, cheap and safe components (i.e. sunflower oil, deionized water, dishwashing liquid and gelatin), we produced and tested, both dielectrically and mechanically, more than 100 samples. The dielectric properties were measured from 500 MHz to 14 GHz, the Cole-Cole parameters were derived to describe the dielectric behaviour in a broader frequency range, and the results were compared with dielectric properties of human breastex vivotissues up to 50 GHz. The macroscale mechanical properties were measured by means of unconfined compression tests, and the impact of the experimental conditions (i.e. preload and test speed) on the measured Young's moduli was analysed. In addition, the mechanical contrast between healthy- and malignant-tissue-like phantoms was evaluated.Main results. The results agree with the literature in the cases in which the experimental conditions are known, demonstrating the possibility to fabricate phantoms able to mimic both dielectric and mechanical properties of breast tissues.Significance. In this work, for the first time, a range of materials reproducing all the categories of breast tissues were experimentally characterized, both from a dielectric and mechanical point of view. A large range of frequency were considered for the dielectric measurements and several combinations of experimental conditions were investigated in the context of the mechanical characterization. The proposed results can be useful in the design and testing of complementary or supplementary techniques for breast cancer detection based on micro/millimetre-waves, possibly in connection with other imaging modalities.

Keywords: Young’s modulus; bi- and multi-modal imaging; breast cancer detection; dielectric properties; mechanical properties; microwave and millimetre wave imaging; tissue-mimicking phantoms.