Endoscopic biliary drainage using a 4-Fr catheter for biliary obstruction: a pilot study

Minim Invasive Ther Allied Technol. 2022 Oct;31(7):1035-1040. doi: 10.1080/13645706.2022.2090004. Epub 2022 Jun 22.

Abstract

Introduction: Stent or endoscopic nasobiliary drainage (ENBD) catheter placement for a tight, complicated biliary stricture is still technically challenging. A thin, 4-Fr ENBD catheter (4-Fr catheter) has been developed to overcome this difficulty. The study aimed to evaluate the feasibility of the 4-Fr catheter for endoscopic biliary drainage (EBD).

Material and methods: We performed a retrospective review of 51 patients who underwent EBD with the 4-Fr catheter because placement of a conventional drainage catheter (CDC) had failed.

Results: The success rate of 4-Fr catheter placement was 96.1% (49/51). The median patency period of the catheter was 114 days (95% CI, 53-200). Among the 49 patients with successful placement of the catheter, adverse events occurred in five (10.2%) patients: post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP), two patients; catheter dislocation, one patient; and kinking of the 4-Fr catheter, two patients. Both cases of PEP improved with conservative treatment, but all cases of catheter dislocation and kinking required reintervention with a 4-Fr catheter. Forty-three (87.8%) patients achieved clinical remission after EBD with a 4-Fr catheter.

Conclusions: The newly developed 4-Fr catheter is safe and feasible for EBD in patients in whom CDC placement is difficult due to a tight, complicated biliary stricture.

Keywords: 4-Fr catheter; Endoscopic biliary drainage; endoscopic biliary stenting; endoscopic nasobiliary drainage; tight biliary strictures.

MeSH terms

  • Catheters
  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects
  • Cholestasis* / etiology
  • Cholestasis* / surgery
  • Constriction, Pathologic
  • Drainage* / adverse effects
  • Humans
  • Pilot Projects
  • Retrospective Studies
  • Stents / adverse effects
  • Treatment Outcome