Outcomes of Oral and Oropharyngeal Squamous Cell Carcinoma Related to Healthcare Coverage: A Retrospective Cohort Study in Brazil

Cancer Invest. 2022 Sep;40(8):680-692. doi: 10.1080/07357907.2022.2092634. Epub 2022 Jun 26.

Abstract

We investigated the differences in prognosis according to the type of healthcare coverage of patients with oral and oropharyngeal squamous cell carcinoma (OOSCC). This study included 875 medical records. Patients covered by the publicly funded Unified Health System (SUS) had a low educational level, with advanced T stage and delayed treatment initiation. Multivariate analyses revealed an association between T stage (p = .035) and poor prognosis in oral squamous cell carcinoma, and age (p = .029) in oropharyngeal squamous cell carcinoma. Surgical treatment (p = .036) and marital status (p = .015) were considered predictors of better prognosis in OOSCC. Exclusive SUS-dependency can be considered an indirect prognostic factor for OOSCC.

Keywords: Mouth neoplasms; oropharyngeal neoplasms; survival analysis; universal health insurance.

MeSH terms

  • Brazil / epidemiology
  • Carcinoma, Squamous Cell* / pathology
  • Delivery of Health Care
  • Head and Neck Neoplasms*
  • Humans
  • Mouth Neoplasms* / pathology
  • Oropharyngeal Neoplasms* / therapy
  • Prognosis
  • Retrospective Studies
  • Squamous Cell Carcinoma of Head and Neck / therapy