Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater

Emerg Infect Dis. 2022 Jul;28(7):1475-1479. doi: 10.3201/eid2807.220219.

Abstract

Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such experiments can improve understanding of factors associated with norovirus survival in coastal waters and shellfish.

Keywords: France; Norovirus; United States; enteric infections; food safety; human intestinal enteroids; marine environment; persistence; stability; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caliciviridae Infections*
  • Communicable Diseases*
  • Humans
  • Norovirus* / genetics
  • Seawater
  • Shellfish