Natural History of and Dynamic Changes in Clinical Manifestation, Serology, and Treatment of Brucellosis, China

Emerg Infect Dis. 2022 Jul;28(7):1460-1465. doi: 10.3201/eid2807.211766.

Abstract

Serum agglutination test plus exposure history were used to diagnose most cases of human brucellosis in 2 China provinces. After appropriate treatment, 13.3% of acute brucellosis cases progressed to chronic disease; arthritis was an early predictor. Seropositivity can persist after symptoms disappear, which might cause physicians to subjectively extend therapeutic regimens.

Keywords: Brucella; China; bacteria; brucellosis; dynamic surveillance; zoonoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agglutination Tests
  • Antibodies, Bacterial
  • Brucella*
  • Brucellosis* / diagnosis
  • Brucellosis* / drug therapy
  • Brucellosis* / epidemiology
  • China / epidemiology
  • Hematologic Tests
  • Humans

Substances

  • Antibodies, Bacterial