Heteroatom doping plays a crucial role in improving the electrocatalytic performance of catalysts towards water splitting. Owing to the existence of Ru-O moieties, Ru is thus emerging as an ideal dopant for promoting the electrocatalytic performance for water splitting by modifying the electronic structure, introducing extra active sites, improving electronic conductivity, and inducing a strong synergistic effect. Benefitting from these advantages, Ru-doped nanomaterials have been widely investigated and employed as advanced electrocatalysts for water splitting, and many excellent Ru-doped electrocatalysts have been successfully developed. In an effort to obtain a better understanding of the influence of Ru doping on the electrocatalytic water splitting performance of nanocatalysts, we herein summarize the recent progress of Ru-doped electrocatalysts by focusing on the synthesis strategies and advantageous merits. Applications of these new materials in water electrolysis technology are also discussed with emphasis on future directions in this active field of research.