Is there a role of epigenetics in gut microbiome and neurological disorders?

Abstract

Cross-talk between gut microbiota and the nervous system in the pathophysiology of neurological diseases has become a recent focus of interest. The underlying mechanisms are complex, and we suggest that they might involve gut bacterial metabolite-induced epigenetic modulations of neurodegenerative disorders. Advances in epigenetic techniques could provide the key to understanding the epigenetics of the gut-brain axis.

Keywords: Gut microbiota; epigenetics; gut-brain axis; neurodegenerative disorders.