Application Progress of High-Throughput Sequencing Technology in Forensic Diatom Detection

Fa Yi Xue Za Zhi. 2022 Feb 25;38(1):20-30. doi: 10.12116/j.issn.1004-5619.2021.410807.
[Article in English, Chinese]

Abstract

Diatom detection is an important method for identifying drowning and throwing corpses after death and inferring the drowning sites in forensic examination of corpses in water. In recent years,high-throughput sequencing technology has achieved rapid development and has been widely used in research related to diatom taxonomic investigations. This paper reviews the research status and prospects of high-throughput sequencing technology and its application in forensic diatom detection.

硅藻检验是法医学水中尸体检验中鉴别生前溺水与死后抛尸、推断落水地点的重要手段,以硅藻DNA为主要研究对象的分子生物学技术成为硅藻检验的重要技术途径之一。近年来,高通量测序技术获得了较快发展,已被广泛应用于硅藻分类调查。本文对高通量测序技术及其在法医学硅藻检验中的研究和应用现状及前景进行综述。.

Keywords: diatoms; drowning; forensic pathology; high-throughput sequencing; molecular species identification; review.

Publication types

  • Review

MeSH terms

  • Cadaver
  • Diatoms* / genetics
  • Drowning* / diagnosis
  • Forensic Pathology / methods
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Lung
  • Technology