Associations between concentrations of typical ultraviolet filter benzophenones in indoor dust and human hair from China: A human exposure study

Abstract

Benzophenone-3 (BP-3) has been widely used as a typical ultraviolet (UV) filter in various personal care products. While BP-3 and its derivatives (BPs) have been detected in various environmental matrices, very little is known about the concentration profile of BPs in human hair. The associations of BPs in human hair with those in indoor dust samples collected from the same locations remain largely unclear. In this study, a total of 258 indoor dust samples and 66 human hair samples were collected across China and analyzed to determine the presence of BP-3 and its derivatives. The BP-3 concentrations ranged from 0.386 to 1230 ng/g dw in indoor dust and from 0.149 to 696 ng/g dw in human hair. No difference was found between BPs in indoor dust samples from different geographic regions (p > 0.05), whereas relatively higher BP concentrations were observed for dust from urban regions than dust from rural ones (p < 0.05). A positive correlation was found between the BP-3 concentrations of indoor dust and human hair samples (p < 0.05). The estimated daily intake (EDI) of BPs for humans from indoor dust showed a gender difference (females > males; p < 0.05), with the highest EDI value being found in Southwest China (males: 35.5 pg/kg bw/day; females: 40.6 pg/kg bw/day). This study provides the concentration profiles of BPs in human hair and elucidates the associations between the BP concentrations in indoor dust samples and human hair samples collected across China.

Keywords: Association; Benzophenone; Human exposure; Human hair; Indoor dust.