Sensitivity of Various Case Detection Algorithms for Community-based Tuberculosis Screening

Clin Infect Dis. 2023 Feb 8;76(3):e987-e989. doi: 10.1093/cid/ciac492.

Abstract

Using data from 388 people diagnosed with tuberculosis through a community-based screening program in Lima, Peru, we estimated that cough screening followed by sputum smear microscopy would have detected only 23% of cases found using an algorithm of radiographic screening followed by rapid nucleic acid amplification testing and clinical evaluation.

Keywords: TB diagnosis; TB diagnostic algorithm; active case finding; community screening.

MeSH terms

  • Algorithms
  • Humans
  • Mass Screening
  • Mycobacterium tuberculosis* / genetics
  • Nucleic Acid Amplification Techniques
  • Peru / epidemiology
  • Sensitivity and Specificity
  • Sputum
  • Tuberculosis* / diagnosis