Mortality of people with AIDS in Italy: comparison of AIDS surveillance and multiple cause-of-death registries

Francesco Grippo; Enrico Grande; Antonella Zucchetto; Luisa Frova; Marilena Pappagallo; Lucia Pugliese; Vincenza Regine; Diego Serraino; Martina Taborelli; Barbara Suligoi

doi:10.4415/ANN_22_02_10

Mortality of people with AIDS in Italy: comparison of AIDS surveillance and multiple cause-of-death registries

Ann Ist Super Sanita. 2022 Apr-Jun;58(2):139-145. doi: 10.4415/ANN_22_02_10.

Affiliations

¹ Servizio Sistema integrato salute, assistenza e previdenza, Istituto Nazionale di Statistica, Rome, Italy.
² Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
³ Centro Operativo AIDS, Istituto Superiore di Sanità, Rome, Italy.

PMID: 35722801
DOI: 10.4415/ANN_22_02_10

Abstract

Aims: To assess whether the use of multiple cause-of-death data could improve reporting of AIDS mortality in Italy.

Method: Population-based, record-linkage study, on 3,975,431 deaths recorded in the National Registry of Causes of Death (RCoD) and 4,530 deaths recorded in the National AIDS Registry (RAIDS), during 2006-2012.

Results: The record-linkage identified 3,646 AIDS-related deaths present in both registries, 884 deaths in the RAIDS without mention of HIV/AIDS in the RCoD, and 3,796 deaths in the RCoD with mention of HIV/AIDS that were not present in the RAIDS. In the latter, in-depth analysis of multiple cause-of-death allowed the identification of 1,484 deaths that were AIDS-related. On these results, we estimated 6,014 deceased people with AIDS. Of them, 14.7% (884) were not present in the RCoD and 24.7% (1,484) derived from the RCoD only.

Conclusions: The integration of different nationwide registries allowed a more comprehensive estimate of the impact of AIDS-associated mortality in Italy.

MeSH terms

Acquired Immunodeficiency Syndrome* / epidemiology
Cause of Death
Humans
Italy / epidemiology
Registries