Uncommon and Difficult High-Grade Endometrial Carcinomas

Abstract

This article presents features of uncommon high-grade endometrial carcinomas that often pose a significant diagnostic challenge. An update on undifferentiated and dedifferentiated endometrial carcinoma is first provided, followed by discussions on more recently defined entities such as mesonephric-like carcinoma of the endometrium and gastric-type endometrial carcinomas. Finally, endometrial carcinoma with germ cell or trophoblastic-like components is discussed.

Keywords: Dedifferentiated endometrial carcinoma; Endometrial carcinoma with germ cell or trophoblastic-like components; Gastric-type endometrial carcinoma; Mesonephric-like carcinoma of the endometrium; Undifferentiated endometrial carcinoma.