Retroperitoneal and Mesenteric Liposarcomas

Surg Oncol Clin N Am. 2022 Jul;31(3):399-417. doi: 10.1016/j.soc.2022.03.005.

Abstract

Retroperitoneal liposarcomas are a rare entity and are comprised mostly of the well-differentiated and dedifferentiated subtypes. Eight-year survival ranges from 30% to 80% depending on histologic subtype and grade. Surgery is the cornerstone of treatment and compartment resection is the current standard. Mesenteric liposarcomas are extremely rare and comprise more high-grade lesions, with poorer prognosis of 50% 5-year overall survival. They are managed with a similar aggressive surgical approach. This review presents the current management of retroperitoneal and mesenteric liposarcomas.

Keywords: Dedifferentiated liposarcoma; Liposarcoma; Mesenteric liposarcoma; Retroperitoneal liposarcoma; Well-differentiated liposarcoma.

Publication types

  • Review

MeSH terms

  • Humans
  • Liposarcoma* / pathology
  • Liposarcoma* / surgery
  • Retroperitoneal Neoplasms* / pathology
  • Retroperitoneal Neoplasms* / surgery