Towards 'end-to-end' analysis and understanding of biological timecourse data

Biochem J. 2022 Jun 17;479(11):1257-1263. doi: 10.1042/BCJ20220053.

Abstract

Petabytes of increasingly complex and multidimensional live cell and tissue imaging data are generated every year. These videos hold large promise for understanding biology at a deep and fundamental level, as they capture single-cell and multicellular events occurring over time and space. However, the current modalities for analysis and mining of these data are scattered and user-specific, preventing more unified analyses from being performed over different datasets and obscuring possible scientific insights. Here, we propose a unified pipeline for storage, segmentation, analysis, and statistical parametrization of live cell imaging datasets.

Keywords: bioinformatics; live-cell imaging; machine learning.

MeSH terms

  • Datasets as Topic*