Objective: To observe the clinical effect of acupuncture for perimenopausal early-wake insomnia.
Methods: A total of 60 patients with perimenopausal early-wake insomnia were randomly divided into an observation group (30 cases, 3 cases dropped off) and a control group (30 cases, 2 cases dropped off, 2 cases were removed). In the observation group, acupuncture was applied at Baihui (GV 20), Yintang (GV 24+), Anmian (Extra), Hegu (LI 4), Shenmen (HT 7), Taichong (LR 3), Taixi (KI 3), etc., once every other day, 3 times a week. In the control group, oryzanol tablets were taken orally, 20 mg each time, 3 times a day. Both groups were treated for 4 weeks. Before and after treatment, the sleep actigraphy (ACT) was used to measure the effective sleep time, sleep quality, wake-up time, wake-up frequency, each wake-up time, and the Pittsburgh sleep quality index (PSQI) score and early-wake score were compared in the two groups, and the clinical effect was assessed.
Results: After treatment, compared before treatment, the effective sleep time was prolonged and the sleep quality was improved (P<0.05), the wake-up time, each wake-up time were shortened and wake-up frequency was decreased (P<0.05), the PSQI score and early-wake score were decreased (P<0.05) in the observation group. After treatment, the wake-up frequency, PSQI score and early-wake score were decreased in the control group (P<0.05). The effective sleep time, sleep quality, wake-up time, wake-up frequency, each wake-up time, PSQI score and early-wake score after treatment in the observation group were superior to the control group (P<0.05). The total effective rate was 88.9% (24/27) in the observation group, which was higher than 38.5% (10/26) in the control group (P<0.05).
Conclusion: Acupuncture can increase the effective sleep time and improve sleep quality in patients with perimenopausal early-wake insomnia.
目的：观察针刺治疗围绝经期早醒型失眠的临床疗效。方法：将60例围绝经期早醒型失眠患者随机分为观察组（30例，脱落3例）和对照组（30例，脱落2例、剔除2例）。观察组予针刺治疗，穴取百会、印堂、安眠、合谷、神门、太冲、太溪等，隔日1次，每周3次；对照组予谷维素片口服，每次20 mg，每日3次，两组均治疗4周。采用睡眠体动记录仪（ACT）检测两组患者治疗前后有效睡眠时间、睡眠质量、觉醒时间、觉醒次数、每次觉醒时间，比较两组患者治疗前后匹兹堡睡眠质量指数（PSQI）评分及早醒评分，并评定临床疗效。结果：与治疗前比较，治疗后观察组有效睡眠时间延长、睡眠质量升高（P<0.05），觉醒时间及每次觉醒时间缩短、觉醒次数减少（P<0.05），PSQI评分、早醒评分降低（P<0.05）；对照组觉醒次数减少、PSQI评分及早醒评分降低（P<0.05）。治疗后，观察组有效睡眠时间、睡眠质量、觉醒时间、觉醒次数、每次觉醒时间及PSQI评分、早醒评分均优于对照组（P<0.05）。观察组总有效率为88.9%（24/27），高于对照组的38.5%（10/26，P<0.05）。结论：针刺治疗可增加围绝经期早醒型失眠患者有效睡眠时间，提高睡眠质量。.
Keywords: Pittsburgh sleep quality index (PSQI); acupuncture; perimenopausal early-wake insomnia; sleep actigraphy; sleep-wake state.