A Systematic Review of the Treatment Outcomes among Prostate Cancer Patients in Africa

Cancer Invest. 2022 Sep;40(8):722-732. doi: 10.1080/07357907.2022.2091777. Epub 2022 Jun 24.

Abstract

Prostate cancer (PCa) is associated with a significant public health burden in Africa. This systematic review aimed to assess treatment outcomes among PCa patients in Africa. A systematic search of the literature was conducted from 1 December 2021 to 31 March 2022 to identify relevant published studies. PubMed, EMBASE, CINAHL, and Google Scholar databases were used. Twenty-four studies met the inclusion criteria, and the mean age was 68 years. Localized and locally advanced diseases had relatively higher overall survival than metastatic diseases. In metastatic disease, the mean overall five-year survival was 42% which is shorter than the Asian population (61.9%).

Keywords: Africa; Treatment outcomes; prostate cancer; systematic review.

Publication types

  • Systematic Review

MeSH terms

  • Africa / epidemiology
  • Aged
  • Humans
  • Male
  • Prostatic Neoplasms* / pathology
  • Treatment Outcome