Metal-Organic Frameworks-Based Sensors for the Detection of Toxins in Food: A Critical Mini-Review on the Applications and Mechanisms

Xiaoxu Xuan; Mengjie Wang; Sivakumar Manickam; Grzegorz Boczkaj; Joon Yong Yoon; Xun Sun

doi:10.3389/fbioe.2022.906374

Metal-Organic Frameworks-Based Sensors for the Detection of Toxins in Food: A Critical Mini-Review on the Applications and Mechanisms

Front Bioeng Biotechnol. 2022 May 26:10:906374. doi: 10.3389/fbioe.2022.906374. eCollection 2022.

Authors

Xiaoxu Xuan^{1

2}, Mengjie Wang^{1

2}, Sivakumar Manickam³, Grzegorz Boczkaj^{4

5}, Joon Yong Yoon⁶, Xun Sun^{1

2

7}

Affiliations

¹ Key Laboratory of High Efficiency and Clean Mechanical Manufacture, Ministry of Education, School of Mechanical Engineering, Shandong University, Jinan, China.
² National Demonstration Center for Experimental Mechanical Engineering Education, Shandong University, Jinan, China.
³ Petroleum and Chemical Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam.
⁴ Department of Sanitary Engineering, Faculty of Civil and Environmental Engineering, Gdańsk University of Technology, Gdańsk, Poland.
⁵ Advanced Materials Center, Gdansk University of Technology, Gdansk, Poland.
⁶ Department of Mechanical Engineering, BK21 FOUR ERICA-ACE Center, Hanyang University, Ansan, South Korea.
⁷ Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.

Abstract

Using scientific technologies to detect toxins in food is significant to prevent food safety problems and protect people's health. Recently, the rise of sensors has made rapid, efficient, and safe detection of food toxins possible. One of the key factors impacting the sensor's performance is the nanomaterials employed. Metal-organic frameworks (MOFs), with high specific surface area, tunable composition, porous structure, and flexible properties, have aroused the interest of researchers. The applications of MOFs in detecting food toxins have seen remarkable success in the past few years. In this critical mini-review, the impact of various synthesis methods on MOFs' properties is first presented. Then, the applications and mechanisms of MOFs-based sensors in detecting various toxins are summarized and analyzed. Finally, future perspectives, potential opportunities, and challenges in this field are discussed.

Keywords: food safety; metal–organic framework; sensors; synthesis; toxin.

Publication types

Review