Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up

Frank Mei; Lin He; Parsha Forouzan; Ronald Mancini; Robert Nick Hogan

doi:10.1016/j.ajoc.2022.101602

Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up

Am J Ophthalmol Case Rep. 2022 Jun 7:27:101602. doi: 10.1016/j.ajoc.2022.101602. eCollection 2022 Sep.

Authors

Frank Mei¹, Lin He², Parsha Forouzan¹, Ronald Mancini¹, Robert Nick Hogan^{1

2}

Affiliations

¹ Department of Ophthalmology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USA.
² Department of Pathology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USA.

Abstract

Purpose: We report a case with over 6 years of follow-up for well-differentiated liposarcoma or atypical lipomatous tumor (WDL/ALT).

Observations: Over a 6-year time course, a patient with a recurrent right orbital mass was biopsied/debulked four times. It was not until the fourth biopsy that a diagnosis of WDL/ALT was obtained. Throughout the time course, the patient maintained good vision and there has been no evidence of dedifferentiation or metastasis thus far.

Conclusions: The diagnosis of WDL/ALT sound be considered in the cases of a recurrent orbit mass when pathology continually shows nonspecific fibrofatty tissue with chronic inflammatory changes.

Keywords: Liposarcoma; Ocular pathology; Oculoplastic; Orbital mass; Proptosis.

Publication types

Case Reports