Reasons given for non-vaccination and under-vaccination of children and adolescents in sub-Saharan Africa: A systematic review

Hum Vaccin Immunother. 2022 Nov 30;18(5):2076524. doi: 10.1080/21645515.2022.2076524. Epub 2022 Jun 16.

Abstract

To achieve the full benefits of vaccination, it is key to understand the underlying causes of low vaccination by researching the barriers to vaccination at a local level. This systematic literature review aims to identify the reasons given by community members for the non-vaccination and under-vaccination of children and adolescents in sub-Saharan Africa. PubMed, Web of Science, PsycINFO, African Index Medicus, and African Journals Online databases were searched to identify articles published between 2010 and 2020. A total of 37 articles were included. As 17 studies did not report the reasons for non-vaccination and under-vaccination separately, we considered these two outcomes as "incomplete vaccination". The most common reasons for incomplete vaccination were related to caregiver's time constraints, lack of knowledge regarding vaccination, the unavailability of vaccines/personnel in healthcare facilities, missed opportunities for vaccination, caregiver's fear of minor side effects, poor access to vaccination services, and caregiver's vaccination beliefs.

Keywords: Sub-Saharan Africa; adolescent; child; reasons; systematic review; vaccination.

Publication types

  • Systematic Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Africa South of the Sahara
  • Child
  • Health Facilities
  • Humans
  • Vaccination* / psychology
  • Vaccines* / adverse effects

Substances

  • Vaccines

Grants and funding

This systematic literature review is part of the ECOVACSEN project, which has received support from the French National Research Agency, as part of the 2020 generic call for projects [ANR-20-CE36-0005-01].