Simplification and Multidimensional Adaptation of the Stratification Tool for Pharmaceutical Care in People Living With HIV

Ann Pharmacother. 2023 Feb;57(2):163-174. doi: 10.1177/10600280221096759. Epub 2022 Jun 15.

Abstract

Background: People living with human immunodeficiency virus (HIV) require specific pharmaceutical care (PC). Although the 2017 Capacity-Motivation-Opportunity (CMO) PC model allows a multidisciplinary approach that focuses on patient needs, it is too complex and presents room for improvement.

Objective: The aim of this study is to simplify and adapt the previous 2017 PC tool through a multidimensional approach to improve HIV patient care, to prove the validity of the model in real-life patients.

Methods: The new PC tool was generated by keeping some of the variables of the 2017 document and conducting a literature search. Content validity was determined by a 2-round Delphi methodology with an expert panel of 42 pharmacists. Consensus for the first and second rounds was defined as ≥70% agreement. The tool generated was validated in 407 real-life patients.

Results: Thirty-seven experts completed the first round of the Delphi survey and 36 the second. No consensus was reached for 3 variables, any of the frequency options and 4 interventions, while the experts agreed not to include 1 intervention in round 1. Consensus to include them was found for all but 1 variable and 1 intervention in round 2. The final tool obtained to select and stratify HIV-positive patients was composed of 9 dimensions divided into 17 variables. The new tool was validated with real-life patients and 3 priority levels were defined.

Conclusions and relevance: We created a new pyramid of score thresholds to classify patients into priority levels. The new tool simplifies the 2017 model and improves its utility to help HIV-positive patients, owing to its multidimensional approach.

Keywords: HIV/AIDS; adherence; motivational interview; pharmaceutical care; stratification.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Consensus
  • Delphi Technique
  • HIV
  • HIV Infections* / drug therapy
  • Humans
  • Pharmaceutical Services*
  • Pharmacists