Dendritic cells (cross)dress for success

Claudia A Rivera; Ana-Maria Lennon-Duménil

doi:10.1016/j.immuni.2022.05.016

Dendritic cells (cross)dress for success

Immunity. 2022 Jun 14;55(6):965-967. doi: 10.1016/j.immuni.2022.05.016.

Authors

Claudia A Rivera¹, Ana-Maria Lennon-Duménil²

Affiliations

¹ Institut Curie, INSERM U932, PSL Research University, 75005 Paris, France.
² Institut Curie, INSERM U932, PSL Research University, 75005 Paris, France. Electronic address: amlennon@curie.fr.

PMID: 35704996
DOI: 10.1016/j.immuni.2022.05.016

Abstract

The relevance of cross-dressing as an antigen presentation mechanism in antitumor responses is not fully understood. In this issue of Immunity, MacNabb et al. (2022) report that dendritic cells use cross-dressing as an effective mechanism to trigger CD8⁺ T cell antitumor immunity.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Antigen Presentation*
CD8-Positive T-Lymphocytes
Cross-Priming
Dendritic Cells*