Remdesivir-induced bradycardia in a 26-year-old patient with COVID-19: a case report

Infection. 2022 Dec;50(6):1605-1613. doi: 10.1007/s15010-022-01854-3. Epub 2022 Jun 14.

Abstract

Purpose: Remdesivir is the first line hospital treatment of the SARS-CoV-2 infection. Despite its widespread use during COVID-19 pandemic, a limited number of data, also conflicting, are available about the frequency of cardiological side-effects. Additionally, identification of patients who belong to the risk groups for cardiovascular complications of antiviral treatment is difficult.

Case description: Case description We present a case of a 26 year old patient, a soldier with COVID-19 and no comorbidities, who developed marked sinus bradycardia during remdesivir therapy. The bradycardia resolved few days after the end of antiviral treatment.

Conclusion: Our case emphasizes the key importance of the correct monitoring of patients receiving remdesivir, even those who do not have pre-existing heart conditions.

Keywords: Bradycardia; COVID-19; ECG; Remdesivir; SARS-CoV-2.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antiviral Agents / adverse effects
  • Bradycardia / chemically induced
  • COVID-19 Drug Treatment*
  • Humans
  • Pandemics
  • SARS-CoV-2

Substances

  • remdesivir
  • Antiviral Agents