Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia

Drug Des Devel Ther. 2022 Jun 7:16:1731-1741. doi: 10.2147/DDDT.S365292. eCollection 2022.

Abstract

Tumor-associated anorexia, mainly including cancerous anorexia and chemotherapy-induced anorexia, severely reduces the life quality of cancer patients but lacks of effective control until now. Liujunzi decoction (LJZD), a classical tonifying formula in traditional Chinese medicine, has promising effect in preventing and treating many kinds of anorexia. A growing number of evidence showed that LJZD is able to improve tumor-associated anorexia. Up to March 2022, a total of 58 articles studying LJZD or Rikkunshito (the name of LJZD in Japanese herbal medicine) in the treatment of tumor-associated anorexia are searched out in PubMed. This paper summarizes the effect of LJZD in ameliorating tumor-associated anorexia, in order to provide a theoretical basis for the clinical application of LJZD in treating tumor-associated anorexia, laying foundation for further research.

Keywords: Liujunzi decoction; review; tumor-associated anorexia.

Publication types

  • Review

MeSH terms

  • Anorexia / drug therapy
  • Anorexia / etiology
  • Drugs, Chinese Herbal* / pharmacology
  • Humans
  • Medicine, Chinese Traditional
  • Neoplasms* / complications
  • Neoplasms* / drug therapy
  • Phytotherapy

Substances

  • Drugs, Chinese Herbal
  • liujunzi

Grants and funding

This study was supported by the National Natural Science Foundation of China NO.82174143.