Cognitive function is associated with home discharge in subacute stroke patients: a retrospective cohort study

BMC Neurol. 2022 Jun 13;22(1):219. doi: 10.1186/s12883-022-02745-8.

Abstract

Aim: To investigate the cognitive function and its relation to the home discharge of patients following subacute stroke.

Methods: This retrospective cohort study included 1,229 convalescent patients experiencing their first subacute stroke. We determined discharge destination and demographic and clinical information. We recorded the following measurement scores: Mini-Mental State Examination (MMSE) score, Stroke Impairment Assessment Set score, grip strength, and Functional Independence Measure (FIM). We performed a multivariable logistic regression analysis with the forced-entry method to identify factors related to home discharge.

Results: Of the 1,229 participants (mean age: 68.7 ± 13.5 years), 501 (40.8%), 735 (59.8%), and 1,011 (82.3%) were female, had cerebral infarction, and were home discharged, respectively. Multivariable logistic regression analysis revealed that age (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.91 - 0.96; P < 0.001), duration from stroke onset to admission (OR, 0.98; 95% CI, 0.96 - 0.99; P = 0.003), living situation (OR, 4.40; 95% CI, 2.69 - 7.20; P < 0.001), MMSE score at admission (OR, 1.05; 95% CI, 1.00 - 1.09; P = 0.035), FIM motor score at admission (OR, 1.04; 95% CI, 1.01 - 1.06; P = 0.001), and FIM cognitive score at admission (OR, 1.08; 95% CI, 1.04 - 1.13; P < 0.001) were significantly associated with home discharge.

Conclusions: MMSE at admission is significantly associated with home discharge in patients with subacute stroke.

Keywords: Cognitive function; Cognitive impairment; Discharge destination; Retrospective cohort study; Stroke.

MeSH terms

  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Cognition
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patient Discharge
  • Recovery of Function
  • Retrospective Studies
  • Stroke Rehabilitation*
  • Stroke*