Photocatalytic C(sp3) radical generation via C-H, C-C, and C-X bond cleavage

Chia-Yu Huang; Jianbin Li; Chao-Jun Li

doi:10.1039/d2sc00202g

Photocatalytic C(sp³) radical generation via C-H, C-C, and C-X bond cleavage

Chem Sci. 2022 Apr 18;13(19):5465-5504. doi: 10.1039/d2sc00202g. eCollection 2022 May 18.

Authors

Chia-Yu Huang¹, Jianbin Li¹, Chao-Jun Li¹

Affiliation

¹ Department of Chemistry, FRQNT Centre for Green Chemistry and Catalysis, McGill University 801 Sherbrooke Street W. Montreal Quebec H3A 0B8 Canada cj.li@mcgill.ca.

Abstract

C(sp³) radicals (R˙) are of broad research interest and synthetic utility. This review collects some of the most recent advancements in photocatalytic R˙ generation and highlights representative examples in this field. Based on the key bond cleavages that generate R˙, these contributions are divided into C-H, C-C, and C-X bond cleavages. A general mechanistic scenario and key R˙-forming steps are presented and discussed in each section.

Publication types

Review