Advances and Prospects in Antibacterial-Osteogenic Multifunctional Dental Implant Surface

Zixuan Wang; Baosheng Li; Qing Cai; Xiaoyu Li; Zhaoyi Yin; Birong Li; Zhen Li; Weiyan Meng

doi:10.3389/fbioe.2022.921338

Advances and Prospects in Antibacterial-Osteogenic Multifunctional Dental Implant Surface

Front Bioeng Biotechnol. 2022 May 24:10:921338. doi: 10.3389/fbioe.2022.921338. eCollection 2022.

Authors

Zixuan Wang^{1

2}, Baosheng Li¹, Qing Cai¹, Xiaoyu Li¹, Zhaoyi Yin¹, Birong Li¹, Zhen Li¹, Weiyan Meng¹

Affiliations

¹ Department of Dental Implantology, Hospital of Stomatology, Jilin University, Changchun, China.
² Jilin Provincial Key Laboratory of Oral Biomedical Engineering, Changchun, China.

Abstract

In recent years, dental implantation has become the preferred protocol for restoring dentition defects. Being the direct contact between implant and bone interface, osseointegration is the basis for implant exerting physiological functions. Nevertheless, biological complications such as insufficient bone volume, poor osseointegration, and postoperative infection can lead to implant failure. Emerging antibacterial-osteogenic multifunctional implant surfaces were designed to make up for these shortcomings both during the stage of forming osseointegration and in the long term of supporting the superstructure. In this mini-review, we summarized the recent antibacterial-osteogenic modifications of the dental implant surface. The effects of these modifications on biological performance like soft tissue integration, bone osteogenesis, and immune response were discussed. In addition, the clinical findings and prospects of emerging antibacterial-osteogenic implant materials were also discussed.

Keywords: antibacterial; dental implant; immunity; osseointegration; osteogenesis; soft tissue integration; surface modification.

Publication types

Review