Multisystem Inflammatory Syndrome in Children During Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta and Omicron Variant Circulation-United States, July 2021-January 2022

Allison D Miller; Anna R Yousaf; Ethan Bornstein; Michael J Wu; Katherine Lindsey; Michael Melgar; Matthew E Oster; Laura D Zambrano; Angela P Campbell

doi:10.1093/cid/ciac471

Multisystem Inflammatory Syndrome in Children During Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta and Omicron Variant Circulation-United States, July 2021-January 2022

Clin Infect Dis. 2022 Oct 3;75(Suppl 2):S303-S307. doi: 10.1093/cid/ciac471.

Authors

Affiliations

¹ CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
² Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ Northwest Portland Area Indian Health Board, Portland, Oregon, USA.
⁴ Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia.

Abstract

We describe 2116 multisystem inflammatory syndrome in children (MIS-C) cases reported to the Centers for Disease Control and Prevention during Delta and Omicron circulation from July 2021 through January 2022. Half of MIS-C patients were aged 5-11 years, 52% received intensive care unit-level care, and 1.1% died. Only 3.0% of eligible patients were fully vaccinated prior to MIS-C onset.

Keywords: COVID-19; child; epidemiology; multisystem inflammatory syndrome in children.

Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022.

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

COVID-19* / complications
Child
Connective Tissue Diseases*
Coronavirus Infections* / epidemiology
Humans
Pandemics
Pneumonia, Viral* / epidemiology
SARS-CoV-2
Systemic Inflammatory Response Syndrome / epidemiology
United States / epidemiology

Supplementary concepts

SARS-CoV-2 variants
pediatric multisystem inflammatory disease, COVID-19 related