A New Compartment Model of COVID-19 Transmission: The Broken-Link Model

Int J Environ Res Public Health. 2022 Jun 3;19(11):6864. doi: 10.3390/ijerph19116864.

Abstract

We propose a new compartment model of COVID-19 spread, the broken-link model, which includes the effect from unconnected infectious links of the transmission. The traditional SIR-type epidemic models are widely used to analyze the spread status, and the models show the exponential growth of the number of infected people. However, even in the early stage of the spread, it is proven by the actual data that the exponential growth did not occur all over the world. We presume this is caused by the suppression of secondary and higher-order transmissions of COVID-19. We find that the proposed broken-link model quantitatively describes the mechanism of this suppression, which leads to the shape of epicurves of confirmed cases are governed by the probability of unconnected infectious links, and the magnitudes of the cases are proportional to expR0 in each infectious surge generated by a virus of the basic reproduction number R0, and is consistent with the actual data.

Keywords: COVID-19; compartment model; delta variant; epidemic model; omicron variant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Basic Reproduction Number
  • COVID-19*
  • Epidemics*
  • Humans
  • Models, Statistical
  • SARS-CoV-2

Grants and funding

This research was supported by The Nippon Foundation—Osaka University Project for Infectious Disease Prevention.