Association between Thyroid Cancer and Weight Change: A Longitudinal Follow-Up Study

Int J Environ Res Public Health. 2022 May 31;19(11):6753. doi: 10.3390/ijerph19116753.

Abstract

Background: The purpose of this study was to evaluate body mass index (BMI) and systolic blood pressure (SBP)/diastolic blood pressure (DBP) between Korean adults who underwent thyroidectomy and comparison groups.

Methods: Data were included from the Korean National Health Insurance Service-Health Screening Cohort (2002-2015). BMI and SBP/DBP were measured before thyroidectomy, 1 and 2 years after thyroidectomy (n = 1995 in study I, n = 2162 in study II), comparing 1:4 matched participants (n = 7980 in study I, n = 8648 in study II). The paired t-test and linear mixed model were used to identify the differences between groups.

Results: DBP in both thyroid cancer II and comparison II group were significantly lower after thyroidectomy than before thyroidectomy. However, the interaction effect of thyroidectomy in study I and study II did not reach statistical significance.

Conclusion: BMI, SBP and DBP were not significantly different between the thyroidectomy group and the matched comparison group.

Keywords: body weight change; hypertension; obesity; thyroid cancer; thyroidectomy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Pressure / physiology
  • Body Mass Index
  • Follow-Up Studies
  • Humans
  • Hypertension*
  • Thyroid Neoplasms* / epidemiology

Grants and funding

The project has been founded in part by a research grant (NRF-2019-R1G1A1099842, NRF-2021-R1C1C1004986) from the National Research Foundation (NRF) of Korea and Hallym University Research Fund, grant number HURF 2021-43.