Antimicrobial second skin using copper nanomesh

Proc Natl Acad Sci U S A. 2022 Jun 14;119(24):e2200830119. doi: 10.1073/pnas.2200830119. Epub 2022 Jun 9.

Abstract

The functional support and advancement of our body while preserving inherent naturalness is one of the ultimate goals of bioengineering. Skin protection against infectious pathogens is an application that requires common and long-term wear without discomfort or distortion of the skin functions. However, no antimicrobial method has been introduced to prevent cross-infection while preserving intrinsic skin conditions. Here, we propose an antimicrobial skin protection platform copper nanomesh, which prevents cross-infectionmorphology, temperature change rate, and skin humidity. Copper nanomesh exhibited an inactivation rate of 99.99% for Escherichia coli bacteria and influenza virus A within 1 and 10 min, respectively. The thin and porous nanomesh allows for conformal coating on the fingertips, without significant interference with the rate of skin temperature change and humidity. Efficient cross-infection prevention and thermal transfer of copper nanomesh were demonstrated using direct on-hand experiments.

Keywords: antimicrobial performance; breathability; copper coating; cross-infection prevention; nanofiber mesh.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents* / pharmacology
  • Copper* / pharmacology
  • Cross Infection* / prevention & control
  • Escherichia coli / drug effects
  • Fingers
  • Humans
  • Influenza A virus / drug effects
  • Metal Nanoparticles*
  • Porosity
  • Skin* / microbiology

Substances

  • Anti-Infective Agents
  • Copper