Application of Traditional Japanese Drug Jidabokuippo in a Modern Society

Hajime Nakae; Yasuhito Irie; Toshiharu Kitamura; Manabu Okuyama

doi:10.3389/fphar.2022.853012

Application of Traditional Japanese Drug Jidabokuippo in a Modern Society

Front Pharmacol. 2022 May 23:13:853012. doi: 10.3389/fphar.2022.853012. eCollection 2022.

Authors

Hajime Nakae¹, Yasuhito Irie¹, Toshiharu Kitamura¹, Manabu Okuyama¹

Affiliation

¹ Department of Emergency and Critical Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.

Abstract

Background: Jidabokuippo (JDI) () has been used in Japan to alleviate contusion-induced swelling and pain since medieval times. Method: This review investigated the effects of JDI on various symptoms in patients with trauma or static blood^[TM1]. The PubMed and Igaku Chuo Zasshi databases were searched until 24 December 2021. We summarize the benefits of applying JDI to inflammatory conditions, including bruises. Results: JDI has been used to resolve blood ^[TM1] stasis, regulate qi in trauma patients, and treat inflammatory swelling and pain caused by rheumatoid arthritis and cellulitis. As the adverse event rate associated with JDI is low (1.3%), JDI is considered a safe drug. Conclusion: JDI can be used to resolve blood^[TM1] stasis in trauma patients without adverse events associated with nonsteroidal anti-inflammatory drugs.

Keywords: adverse event; inflammatory swelling; made-in-Japan; static blood; trauma.

Publication types

Review