Crystalline inclusions in chronic lymphocytic leukemia

Marco P Barros Pinto; Fátima Carriço; J Melo Cristino

doi:10.1016/j.morpho.2022.05.003

Crystalline inclusions in chronic lymphocytic leukemia

Morphologie. 2023 Mar;107(356):156-157. doi: 10.1016/j.morpho.2022.05.003. Epub 2022 Jun 5.

Authors

Marco P Barros Pinto¹, Fátima Carriço², J Melo Cristino³

Affiliations

¹ Hospital Santa Maria (Serviço Patologia Clínica) - Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal; Faculdade Medicina, Universidade de Lisboa, Lisbon, Portugal. Electronic address: marco.pinto@chln.min-saude.pt.
² Hospital Santa Maria (Serviço Patologia Clínica) - Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal.
³ Hospital Santa Maria (Serviço Patologia Clínica) - Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal; Faculdade Medicina, Universidade de Lisboa, Lisbon, Portugal.

PMID: 35676184
DOI: 10.1016/j.morpho.2022.05.003

Abstract

Crystalline inclusions in lymphocytes are unusual in chronic lymphocytic leukemia. They represent crystallized immunoglobulin (most frequently IgM-lambda) and their recognition facilitates the diagnosis of a lymphoproliferative disorder.

Keywords: Chronic lymphocytic leukemia; Crystalline inclusions; Lymphoproliferative disorder.

Publication types

Case Reports

MeSH terms

Humans
Inclusion Bodies
Leukemia, Lymphocytic, Chronic, B-Cell*
Lymphocytes