Research in Pediatric Intensive Care

Andrew Prout; Kathleen L Meert

doi:10.1016/j.pcl.2022.01.015

Research in Pediatric Intensive Care

Pediatr Clin North Am. 2022 Jun;69(3):607-620. doi: 10.1016/j.pcl.2022.01.015.

Authors

Andrew Prout¹, Kathleen L Meert²

Affiliations

¹ Division of Pediatric Critical Care Medicine, Discipline of Pediatrics, Children's Hospital of Michigan, Floor Carls Building, 3901 Beaubien Boulevard, Detroit, MI, 48201, USA; Central Michigan University, Mt. Pleasant, MI, USA. Electronic address: prout2a@cmich.edu.
² Central Michigan University, Mt. Pleasant, MI, USA; Discipline of Pediatrics, Children's Hospital of Michigan, Detroit, MI, USA; Children's Hospital of Michigan, Suite H-07, 3901 Beaubien Boulevard, Detroit, MI 48201, USA.

PMID: 35667764
DOI: 10.1016/j.pcl.2022.01.015

Abstract

Many important clinical questions remain unanswered in the practice of pediatric intensive care due to the lack of high-quality evidence. Although challenges exist in conducting research in pediatric intensive care units, identification of research priorities, interdisciplinary collaborations, innovative trial designs, and the use of common datasets and outcome measures helps to bring new knowledge to our field. The topic of "Research in PICUs" is extremely broad; therefore, this review focuses on a few common themes receiving increased attention in the literature, including research agendas, core outcome sets, precision medicine, and novel clinical trial strategies.

Keywords: Children; Clinical trials; Core outcome sets; Infants; Pediatric intensive care unit; Precision medicine; Research agenda.

Publication types

Review

MeSH terms

Child
Critical Care
Humans
Intensive Care Units, Pediatric*
Outcome Assessment, Health Care*
Precision Medicine