Treatment approach to connective tissue disease-associated interstitial lung disease

Curr Opin Pharmacol. 2022 Aug:65:102245. doi: 10.1016/j.coph.2022.102245. Epub 2022 Jun 1.

Abstract

Interstitial lung disease (ILD) is a common manifestation in connective tissue diseases (CTD), such as rheumatoid arthritis (RA), systemic sclerosis (SSc), and inflammatory myositis (IM). ILD is associated with significant morbidity and mortality in nearly all CTD highlighting the critical need for effective treatment strategies in this patient population. In this review, we will summarize the approach to treatment when there is concern for CTD-ILD and highlight recent advancements in therapeutics within various forms of CTD-ILD.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Arthritis, Rheumatoid*
  • Connective Tissue Diseases* / complications
  • Connective Tissue Diseases* / drug therapy
  • Humans
  • Lung Diseases, Interstitial* / complications
  • Lung Diseases, Interstitial* / etiology
  • Treatment Outcome