Fungal Bloodstream Co-infection by Trichosporon asahii in a COVID-19 Critical Patient: Case Report and Literature Review

Mycopathologia. 2022 Aug;187(4):397-404. doi: 10.1007/s11046-022-00637-6. Epub 2022 Jun 4.

Abstract

Opportunistic infections are serious complications in critically ill COVID-19 patients, especially co-infections with bacterial and fungal agents. Here we report a rare case of bloodstream co-infection by Trichosporon asahii, an emerging yeast, and Acinetobacterbaumannii, an opportunistic nosocomial pathogen, both multidrug resistant, in a tertiary hospital from southern Brazil. A review of the literature regarding similar cases is also included. Treatment with multiple antimicrobials failed, and the patient progressed to death four days after the diagnosis of bacteremia and fungemia.

Keywords: COVID-19 co-infections; Emerging pathogens; Fungemia; Multi-drug resistance; Opportunistic disease; Sepsis; Trichosporon spp..

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Basidiomycota
  • COVID-19* / complications
  • Coinfection* / diagnosis
  • Coinfection* / drug therapy
  • Humans
  • Mycoses* / diagnosis
  • Sepsis* / microbiology
  • Trichosporon*

Substances

  • Antifungal Agents

Supplementary concepts

  • Trichosporon asahii