A new twin expands the VirB8-like protein family

Robine Maffo-Woulefack; Nathalie Leblond-Bourget; Badreddine Douzi

doi:10.1016/j.str.2022.05.004

A new twin expands the VirB8-like protein family

Structure. 2022 Jun 2;30(6):790-792. doi: 10.1016/j.str.2022.05.004.

Authors

Robine Maffo-Woulefack¹, Nathalie Leblond-Bourget¹, Badreddine Douzi²

Affiliations

¹ Université de Lorraine, INRAE, DynAMic, 54000 Nancy, France.
² Université de Lorraine, INRAE, DynAMic, 54000 Nancy, France. Electronic address: badreddine.douzi@inrae.fr.

PMID: 35660242
DOI: 10.1016/j.str.2022.05.004

Abstract

Conjugative transfer is mediated by specialized type IV secretion systems (T4SSs). However, their architecture and mode of function remain poorly defined in Gram-positives. In this issue of Structure, Jäger et al. reveal an exclusive assembly of PrgL and illustrate the importance of its structural organization in pCF10 conjugative transfer.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Bacterial Proteins* / chemistry
Plasmids
Type IV Secretion Systems* / chemistry

Substances

Bacterial Proteins
Type IV Secretion Systems