Sleep Deficiency and Cardiometabolic Disease

Roo Killick; Lachlan Stranks; Camilla M Hoyos

doi:10.1016/j.ccm.2022.02.011

Sleep Deficiency and Cardiometabolic Disease

Clin Chest Med. 2022 Jun;43(2):319-336. doi: 10.1016/j.ccm.2022.02.011.

Authors

Roo Killick¹, Lachlan Stranks², Camilla M Hoyos³

Affiliations

¹ Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia.
² Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia; The University of Adelaide, Faculty of Health and Medical Sciences, Adelaide, Australia.
³ Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia; The University of Sydney, Faculty of Science, School of Psychology and Brain and Mind Centre, Sydney, Australia. Electronic address: camilla.hoyos@sydney.edu.au.

PMID: 35659028
DOI: 10.1016/j.ccm.2022.02.011

Abstract

Epidemiologic studies have demonstrated that short sleep duration is associated with an increased risk of cardio-metabolic health outcomes including cardiovascular disease mortality, coronary heart disease, type 2 diabetes mellitus, hypertension, and metabolic syndrome. Experimental sleep restriction studies have sought to explain these findings. This review describes the main evidence of these associations and possible mechanisms explaining them. Whether sleep extension reverses these now widely acknowledged adverse health effects and the feasibility of implementing such strategies on a public health level is discussed.

Keywords: Cardiometabolic outcomes; Cardiovascular disease; Metabolic health; Sleep deprivation; Sleep restriction.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Cardiovascular Diseases* / complications
Cardiovascular Diseases* / etiology
Diabetes Mellitus, Type 2* / complications
Diabetes Mellitus, Type 2* / epidemiology
Humans
Risk Factors
Sleep
Sleep Wake Disorders* / complications