A Review: Cereals on Modulating the Microbiota/Metabolome for Metabolic Health

Curr Nutr Rep. 2022 Sep;11(3):371-385. doi: 10.1007/s13668-022-00424-1. Epub 2022 Jun 3.

Abstract

Purpose of review: Diet can modulate both the composition and functionality of the human gut microbiota. Cereals are rich in specific macro and functional elements that are considered important dietary components for maintaining human health; therefore, it is important to examine precise nutritional mechanism involved in exerting the health benefits via modulating gut microbiota. The purpose of this review is to summarize recent research on how different cereals in the diet can regulate the microbiota for health and disease.

Recent findings: There is an increased interest in targeting the gut microbiome for the treatment of chronic diseases. Cereals can alter the gut microbiome and may improve energy and glucose homeostasis, interfere with host energy homeostasis, appetite, blood glucose regulation, insulin sensitivity, and regulation of host metabolism. However, more human research is necessary to confirm the beneficial health outcomes of cereals via modulating gut microbiota. Cereals play an essential role in shaping the intestinal microbiota that contributes to exerting health effects on various diseases.

Keywords: Cereals; Colon health; Diabetes; Hyperlipidemia; Hypertension; Inflammation; Metabolites; Obesity; Short-chain fatty acids.

Publication types

  • Review

MeSH terms

  • Diet
  • Edible Grain
  • Gastrointestinal Microbiome*
  • Humans
  • Metabolome / physiology
  • Microbiota*