Information entropy tradeoffs for efficient uncertainty reduction in estimates of air pollution mortality

Environ Res. 2022 Sep;212(Pt D):113587. doi: 10.1016/j.envres.2022.113587. Epub 2022 May 30.

Abstract

Implementing effective policy to protect human health from the adverse effects of air pollution, such as premature mortality, requires reducing the uncertainty in health outcomes models. Here we present a novel method to reduce mortality uncertainty by increasing the amount of input data of air pollution and health outcomes, and then quantifying tradeoffs associated with the different data gained. We first present a study of long-term mortality from fine particulate matter (PM2.5) based on simulated data, followed by a real-world application of short-term PM2.5-related mortality in an urban area. We employ information yield curves to identify which variables more effectively reduce mortality uncertainty when increasing information. Our methodology can be used to explore how specific pollution scenarios will impact mortality and thus improve decision-making. The proposed framework is general and can be applied to any real case-scenario where knowledge in pollution, demographics, or health outcomes can be augmented through data acquisition or model improvements to generate more robust risk assessments.

Keywords: Air pollution; Health risk assessment; Information entropy; Mortality; PM(2.5); Uncertainty quantification.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Air Pollutants* / analysis
  • Air Pollutants* / toxicity
  • Air Pollution*
  • Entropy
  • Humans
  • Particulate Matter / analysis
  • Uncertainty

Substances

  • Air Pollutants
  • Particulate Matter