Polymerization-Induced Hierarchical Electrostatic Self-Assembly: Scalable Synthesis of Multicompartment Polyion Complex Micelles and Their Monolayer Colloidal Nanosheets and Nanocages

Qizhou Liu; Xiyu Wang; Lei Ma; Kaiwen Yu; Weixing Xiong; Xinhua Lu; Yuanli Cai

doi:10.1021/acsmacrolett.0c00090

Polymerization-Induced Hierarchical Electrostatic Self-Assembly: Scalable Synthesis of Multicompartment Polyion Complex Micelles and Their Monolayer Colloidal Nanosheets and Nanocages

ACS Macro Lett. 2020 Apr 21;9(4):454-458. doi: 10.1021/acsmacrolett.0c00090. Epub 2020 Mar 13.

Authors

Qizhou Liu¹, Xiyu Wang¹, Lei Ma¹, Kaiwen Yu¹, Weixing Xiong¹, Xinhua Lu¹, Yuanli Cai¹

Affiliation

¹ State-Local Joint Engineering Laboratory for Novel Functional Polymer Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.

PMID: 35648501
DOI: 10.1021/acsmacrolett.0c00090

Abstract

Scalable synthesis of multicompartment polyion complex (PIC) systems has been achieved via visible light-initiated RAFT polymerization of cationic monomer in the presence of anionic diblock copolymer micelles in water at 25 °C. This polymerization-induced hierarchical electrostatic self-assembly (hierarchical PIESA) implements structural hierarchy via programmable self-assembly to form multicompartment PIC micelles and their monolayer colloidal nanosheets and nanocages. The anionic micelles play decisive roles in such a hierarchical PIESA to access biologically relevant yet otherwise inaccessible multicompartment PIC systems.