Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Aysu Yarman; Sevinc Kurbanoglu

doi:10.3390/biomimetics7020058

Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Biomimetics (Basel). 2022 May 6;7(2):58. doi: 10.3390/biomimetics7020058.

Authors

Aysu Yarman^{1

2}, Sevinc Kurbanoglu³

Affiliations

¹ Molecular Biotechnology, Faculty of Science, Turkish-German University, Sahinkaya Cad. 86, Beykoz, Istanbul 34820, Turkey.
² Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Strasse 24-25, 14476 Potsdam, Germany.
³ Faculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Yenimahalle, Ankara 06560, Turkey.

Abstract

Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has played a major role worldwide. For this reason, various methods have been developed, comprising reverse transcriptase-polymerase chain reaction (RT-PCR), immunoassays, clustered regularly interspaced short palindromic repeats (CRISPR), reverse transcription loop-mediated isothermal amplification (RT-LAMP), and bio(mimetic)sensors. Among the developed methods, RT-PCR is so far the gold standard. Herein, we give an overview of the MIP-based sensors utilized since the beginning of the pandemic.

Keywords: SARS-CoV-2; biomimetic sensors; molecularly imprinted polymers.

Publication types

Review

Grants and funding

This work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC 2008/1 (UniSysCat)—390540038 [Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) im Rahmen der Exzellenzstrategie des Bundes und der Länder—EXC 2008/1 (UniSysCat)—390540038].