Association of Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination or a Prior Positive Test Result in Adolescents during the Delta Variant Surge in Kentucky

Kevin B Spicer; Connor Glick; Alyson M Cavanaugh; Douglas Thoroughman

doi:10.1016/j.jpeds.2022.05.034

Association of Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination or a Prior Positive Test Result in Adolescents during the Delta Variant Surge in Kentucky

J Pediatr. 2022 Sep:248:119-121. doi: 10.1016/j.jpeds.2022.05.034. Epub 2022 May 27.

Authors

Kevin B Spicer¹, Connor Glick², Alyson M Cavanaugh³, Douglas Thoroughman⁴

Affiliations

¹ Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA; Kentucky Department for Public Health, Division of Epidemiology and Health Planning, Frankfort, KY.
² Kentucky Department for Public Health, Division of Epidemiology and Health Planning, Frankfort, KY.
³ Kentucky Department for Public Health, Division of Epidemiology and Health Planning, Frankfort, KY; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA.
⁴ Kentucky Department for Public Health, Division of Epidemiology and Health Planning, Frankfort, KY; Career Epidemiology Field Officer Program, Division of State and Local Readiness, Center for Preparedness and Response, Centers for Disease Control and Prevention, Atlanta, GA.

Abstract

In a cross-sectional study of 89 736 adolescents in Kentucky, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination provided an estimated protection against infection of 81% when the highly transmissible Delta variant was predominant. Vaccination provided added benefit to those with a history of prior infection. These findings support the recommendation that all adolescents receive SARS-CoV-2 vaccination.

Keywords: adolescents; infection-derived immunity; reinfection; vaccine-derived immunity.

Published by Elsevier Inc.

Publication types

Case Reports

MeSH terms

Adolescent
COVID-19 Vaccines
COVID-19* / epidemiology
COVID-19* / prevention & control
Cross-Sectional Studies
Humans
Kentucky / epidemiology
SARS-CoV-2* / genetics
Vaccination

Substances

COVID-19 Vaccines

Supplementary concepts

SARS-CoV-2 variants