Developing a new predictive index for anastomotic leak following the anastomosis of esophageal atresia: preliminary results from a single centre

J Cardiothorac Surg. 2022 May 28;17(1):131. doi: 10.1186/s13019-022-01878-8.

Abstract

Background: The aim of this study was to determine a predictive index for the risk of anastomotic leak following esophageal atresia anastomosis, METHODS: This article reviewed the clinical data of 74 children with esophageal atresia in Fujian Children's hospital. The risk factors for anastomotic leak were analysed, and a new predictive index was proposed.

Results: The incidence of anastomotic leak was 29.7% after anastomosis in 74 children with esophageal atresia. Birth weight and gap length were risk factors for anastomotic leak. Logistic regression analysis showed that birth weight (Wald 2 = 4.528, P = 0.033, OR = 0.273) was a protective factor for anastomotic leak, whereas gap length (Wald 2 = 7.057, P = 0.008, OR = 2.388) was a risk factor for anastomotic leak. The ratio of gap length to birth weight had a positive predictive effect on the occurrence of anastomotic leak (AUC = 0.732, P = 0.002).

Conclusion: Birth weight and gap length are important predictors of anastomotic leak in esophageal atresia. Measurement of the ratio of gap length to birth weight is a helpful predictive index for anastomotic leak following the anastomosis of esophageal atresia.

Keywords: Anastomotic leak; Atresia gap length; Birth weight; Esophageal atresia.

Publication types

  • Review

MeSH terms

  • Anastomosis, Surgical / adverse effects
  • Anastomotic Leak / epidemiology
  • Anastomotic Leak / etiology
  • Birth Weight
  • Child
  • Esophageal Atresia* / surgery
  • Humans
  • Risk Factors