Chemistry and anticancer activity of cardiac glycosides: A review

Chem Biol Drug Des. 2022 Sep;100(3):364-375. doi: 10.1111/cbdd.14096. Epub 2022 Jun 13.

Abstract

The objective of this review is an attempt to emphasize the development in the chemistry and to display review of diverse therapeutic actions of cardiac glycosides. Anticancer activity of cardiac glycosides is the main activity as discussed in this review. The aim of the review is to gather the recent researches on cardiac glycosides. The present manuscript gives the platform for the researcher to have complete literature on the topic.

Keywords: anticancer; cancer cell lines; cardiac glycosides; cytotoxic.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents* / pharmacology
  • Antineoplastic Agents* / therapeutic use
  • Cardiac Glycosides* / pharmacology
  • Cardiac Glycosides* / therapeutic use
  • Glycosides / pharmacology
  • Glycosides / therapeutic use

Substances

  • Antineoplastic Agents
  • Cardiac Glycosides
  • Glycosides