White-centered retinal hemorrhage revealing acute leukemia: A case report

Nadia Ben Abdesslem; Nesrine Zaafrane; Atf Ben Abderazek; Ahmed Jabri; Anis Mahjoub; Chiraz Ben Youssef; Hachemi Mahjoub; Fethi Krifa; Ahmed Mahjoub

doi:10.1016/j.amsu.2022.103632

White-centered retinal hemorrhage revealing acute leukemia: A case report

Ann Med Surg (Lond). 2022 Apr 15:77:103632. doi: 10.1016/j.amsu.2022.103632. eCollection 2022 May.

Authors

Nadia Ben Abdesslem^{1

2}, Nesrine Zaafrane^{1

2}, Atf Ben Abderazek^{1

2}, Ahmed Jabri^{1

2}, Anis Mahjoub^{1

2}, Chiraz Ben Youssef^{1

2}, Hachemi Mahjoub^{1

2}, Fethi Krifa^{1

2}, Ahmed Mahjoub^{1

2}

Affiliations

¹ Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia.
² Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia.

Abstract

Retinal manifestations have been described as an inaugural manifestation of acute leukemia. Retinal hemorrhage, and in particular white-centered hemorrhages are among the most frequently observed signs. We report here the case of a 34-year-old Caucasian man with no medical history who presented to our emergency department with a decrease in visual acuity associated with asthenia. Ophthalmological examination revealed bilateral white-centered hemorrhages. The etiological assessment confirmed the diagnosis of acute myeloid leukemia. Whenever Roth spots are found in fundus examination, a complete ophthalmological examination along with a wide etiological investigation must be conducted.

Keywords: Acute myeloid leukemia; Case report; Roth spots; White-centered hemorrhage.

Publication types

Case Reports